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Melatonin Inhibits Androgen Receptor Splice Variant-7 (AR-V7)-Induced Nuclear Factor-Kappa B (NF-κB) Activation and NF-κB Activator-Induced AR-V7 Expression in Prostate Cancer Cells: Potential Implications for the Use of Melatonin in Castration-Resistant Prostate Cancer (CRPC) Therapy

A major current challenge in the treatment of advanced prostate cancer, which can be initially controlled by medical or surgical castration, is the development of effective, safe, and affordable therapies against progression of the disease to the stage of castration resistance. Here, we showed that...

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Detalles Bibliográficos
Autores principales: Liu, Vincent Wing Sun, Yau, Wing Lung, Tam, Chun Wai, Yao, Kwok-Ming, Shiu, Stephen Yuen Wing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485954/
https://www.ncbi.nlm.nih.gov/pubmed/28561752
http://dx.doi.org/10.3390/ijms18061130