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A Relative Deficiency of Lysosomal Acid Lypase Activity Characterizes Non-Alcoholic Fatty Liver Disease

Lysosomal acid lipase (LAL) is a key enzyme in lipid metabolism. Initial reports have suggested a role for a relative acquired LAL deficiency in non-alcoholic fatty liver disease (NAFLD)—however, it is still unclear whether this mechanism is specific for NAFLD. We aimed to determine LAL activity in...

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Detalles Bibliográficos
Autores principales: Tovoli, Francesco, Napoli, Lucia, Negrini, Giulia, D’Addato, Sergio, Tozzi, Giulia, D’Amico, Jessica, Piscaglia, Fabio, Bolondi, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485958/
https://www.ncbi.nlm.nih.gov/pubmed/28587063
http://dx.doi.org/10.3390/ijms18061134