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Transfection of Antisense Oligonucleotides Mediated by Cationic Vesicles Based on Non-Ionic Surfactant and Polycations Bearing Quaternary Ammonium Moieties

Three different ionene polymers with varying quaternary ammonium moieties were used as a proof of concept for the formulation of antisense oligonucleotides, which are capable of inhibiting Renilla luciferase messenger ribonucleic acid (mRNA). Cationic vesicles, consisting of cationic polymer, antise...

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Detalles Bibliográficos
Autores principales: Mayr, Judith, Grijalvo, Santiago, Bachl, Jürgen, Pons, Ramon, Eritja, Ramon, Díaz Díaz, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485963/
https://www.ncbi.nlm.nih.gov/pubmed/28587106
http://dx.doi.org/10.3390/ijms18061139