Impaired Insulin Signaling is Associated with Hepatic Mitochondrial Dysfunction in IR(+/−)-IRS-1(+/−) Double Heterozygous (IR-IRS1dh) Mice

Mitochondria play a pivotal role in energy metabolism, but whether insulin signaling per se could regulate mitochondrial function has not been identified yet. To investigate whether mitochondrial function is regulated by insulin signaling, we analyzed muscle and liver of insulin receptor (IR)(+/−)-i...

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Detalles Bibliográficos
Autores principales: Franko, Andras, Kunze, Alexander, Böse, Marlen, von Kleist-Retzow, Jürgen-Christoph, Paulsson, Mats, Hartmann, Ursula, Wiesner, Rudolf J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485980/
https://www.ncbi.nlm.nih.gov/pubmed/28556799
http://dx.doi.org/10.3390/ijms18061156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485980/
https://www.ncbi.nlm.nih.gov/pubmed/28556799
http://dx.doi.org/10.3390/ijms18061156

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