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Role of Free Radicals and Biotransformation in Trichloronitrobenzene-Induced Nephrotoxicity In Vitro

This study determined the comparative nephrotoxic potential of four trichloronitrobenzenes (TCNBs) (2,3,4-; 2,4,5-; 2,4,6-; and 3,4,5-TCNB) and explored the effects of antioxidants and biotransformation inhibitors on TCNB-induced cytotoxicity in isolated renal cortical cells (IRCC) from male Fischer...

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Detalles Bibliográficos
Autores principales: Rankin, Gary O., Tyree, Connor, Pope, Deborah, Tate, Jordan, Racine, Christopher, Anestis, Dianne K., Brown, Kathleen C., Dial, Mason, Valentovic, Monica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485989/
https://www.ncbi.nlm.nih.gov/pubmed/28561793
http://dx.doi.org/10.3390/ijms18061165