EZH2 in Cancer Progression and Potential Application in Cancer Therapy: A Friend or Foe?

Enhancer of zeste homolog 2 (EZH2), a histone methyltransferase, catalyzes tri-methylation of histone H3 at Lys 27 (H3K27me3) to regulate gene expression through epigenetic machinery. EZH2 functions as a double-facet molecule in regulation of gene expression via repression or activation mechanisms,...

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Detalles Bibliográficos
Autores principales: Yan, Ke-Sin, Lin, Chia-Yuan, Liao, Tan-Wei, Peng, Cheng-Ming, Lee, Shou-Chun, Liu, Yi-Jui, Chan, Wing P., Chou, Ruey-Hwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485996/
https://www.ncbi.nlm.nih.gov/pubmed/28561778
http://dx.doi.org/10.3390/ijms18061172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485996/
https://www.ncbi.nlm.nih.gov/pubmed/28561778
http://dx.doi.org/10.3390/ijms18061172

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