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Differential Sarcomere and Electrophysiological Maturation of Human iPSC-Derived Cardiac Myocytes in Monolayer vs. Aggregation-Based Differentiation Protocols

Human induced pluripotent stem cells (iPSCs) represent a powerful human model to study cardiac disease in vitro, notably channelopathies and sarcomeric cardiomyopathies. Different protocols for cardiac differentiation of iPSCs have been proposed either based on embroid body formation (3D) or, more r...

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Detalles Bibliográficos
Autores principales: Jeziorowska, Dorota, Fontaine, Vincent, Jouve, Charlène, Villard, Eric, Dussaud, Sébastien, Akbar, David, Letang, Valérie, Cervello, Pauline, Itier, Jean-Michiel, Pruniaux, Marie-Pierre, Hulot, Jean-Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485997/
https://www.ncbi.nlm.nih.gov/pubmed/28587156
http://dx.doi.org/10.3390/ijms18061173