A Tox21 Approach to Altered Epigenetic Landscapes: Assessing Epigenetic Toxicity Pathways Leading to Altered Gene Expression and Oncogenic Transformation In Vitro

An emerging vision for toxicity testing in the 21st century foresees in vitro assays assuming the leading role in testing for chemical hazards, including testing for carcinogenicity. Toxicity will be determined by monitoring key steps in functionally validated molecular pathways, using tests designe...

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Detalles Bibliográficos
Autores principales: Parfett, Craig L., Desaulniers, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486002/
https://www.ncbi.nlm.nih.gov/pubmed/28587163
http://dx.doi.org/10.3390/ijms18061179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486002/
https://www.ncbi.nlm.nih.gov/pubmed/28587163
http://dx.doi.org/10.3390/ijms18061179

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