mtDNA as a Mediator for Expression of Hypoxia-Inducible Factor 1α and ROS in Hypoxic Neuroblastoma Cells

Mitochondria consume O(2) to produce ATP and are critical for adaption of hypoxia, but the role of mitochondria in HIF-1α pathway is as yet unclear. In this study, mitochondrial DNA (mtDNA) enriched (SK-N-AS) and depleted (ρ(0)) cells of neuroblastoma were cultured in a hypoxic chamber to simulate a...

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Detalles Bibliográficos
Autores principales: Kuo, Chung-Wen, Tsai, Meng-Han, Lin, Tsu-Kung, Tiao, Mao-Meng, Wang, Pei-Wen, Chuang, Jiin-Haur, Chen, Shang-Der, Liou, Chia-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486043/
https://www.ncbi.nlm.nih.gov/pubmed/28590414
http://dx.doi.org/10.3390/ijms18061220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486043/
https://www.ncbi.nlm.nih.gov/pubmed/28590414
http://dx.doi.org/10.3390/ijms18061220

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