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Alteration of SHP-1/p-STAT3 Signaling: A Potential Target for Anticancer Therapy

The Src homology 2 (SH2) domain-containing protein tyrosine phosphatase 1 (SHP-1), a non-receptor protein tyrosine phosphatase, has been reported as a negative regulator of phosphorylated signal transducer and activator of transcription 3 (STAT3) and linked to tumor development. In this present revi...

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Detalles Bibliográficos
Autores principales: Huang, Tzu-Ting, Su, Jung-Chen, Liu, Chun-Yu, Shiau, Chung-Wai, Chen, Kuen-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486057/
https://www.ncbi.nlm.nih.gov/pubmed/28594363
http://dx.doi.org/10.3390/ijms18061234