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Hypoxia Inducible Factor-2 Alpha and Prolinhydroxylase 2 Polymorphisms in Patients with Acute Respiratory Distress Syndrome (ARDS)

Hypoxia-inducible-factor-2α (HIF-2α) and HIF-2 degrading prolyl-hydroxylases (PHD) are key regulators of adaptive hypoxic responses i.e., in acute respiratory distress syndrome (ARDS). Specifically, functionally active genetic variants of HIF-2α (single nucleotide polymorphism (SNP) [ch2:46441523(hg...

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Detalles Bibliográficos
Autores principales: Dötsch, Annika, Eisele, Lewin, Rabeling, Miriam, Rump, Katharina, Walstein, Kai, Bick, Alexandra, Cox, Linda, Engler, Andrea, Bachmann, Hagen S., Jöckel, Karl-Heinz, Adamzik, Michael, Peters, Jürgen, Schäfer, Simon T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486088/
https://www.ncbi.nlm.nih.gov/pubmed/28613249
http://dx.doi.org/10.3390/ijms18061266