An Isoform of Nedd4-2 Plays a Pivotal Role in Electrophysiological Cardiac Abnormalities

We have previously shown that neural precursor cell-expressed developmentally downregulated gene 4-2 (Nedd4-2) isoforms with a C2 domain are closely related to ubiquitination of epithelial sodium channel (ENaC), resulting in salt-sensitive hypertension by Nedd4-2 C2 targeting in mice. The sodium vol...

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Detalles Bibliográficos
Autores principales: Minegishi, Shintaro, Ishigami, Tomoaki, Kawamura, Hisho, Kino, Tabito, Chen, Lin, Nakashima-Sasaki, Rie, Doi, Hiroshi, Azushima, Kengo, Wakui, Hiromichi, Chiba, Yumi, Tamura, Kouichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486090/
https://www.ncbi.nlm.nih.gov/pubmed/28613240
http://dx.doi.org/10.3390/ijms18061268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486090/
https://www.ncbi.nlm.nih.gov/pubmed/28613240
http://dx.doi.org/10.3390/ijms18061268

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