CRISPR/Cas9-Mediated Correction of the FANCD1 Gene in Primary Patient Cells

Fanconi anemia (FA) is an inherited condition characterized by impaired DNA repair, physical anomalies, bone marrow failure, and increased incidence of malignancy. Gene editing holds great potential to precisely correct the underlying genetic cause such that gene expression remains under the endogen...

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Detalles Bibliográficos
Autores principales: Skvarova Kramarzova, Karolina, Osborn, Mark J., Webber, Beau R., DeFeo, Anthony P., McElroy, Amber N., Kim, Chong Jai, Tolar, Jakub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486091/
https://www.ncbi.nlm.nih.gov/pubmed/28613254
http://dx.doi.org/10.3390/ijms18061269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486091/
https://www.ncbi.nlm.nih.gov/pubmed/28613254
http://dx.doi.org/10.3390/ijms18061269

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