Autocrine Human Growth Hormone Promotes Invasive and Cancer Stem Cell-Like Behavior of Hepatocellular Carcinoma Cells by STAT3 Dependent Inhibition of CLAUDIN-1 Expression

Despite progress in diagnosis and treatment of hepatocellular carcinoma (HCC), the clinical outcome is still unsatisfactory. Increased expression of human growth hormone (hGH) in HCC has been reported and is associated with poor survival outcome in HCC patients. Herein, we investigated the mechanism...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Jun, You, Ming-Liang, Chong, Qing-Yun, Pandey, Vijay, Zhuang, Qiu-Shi, Liu, Dong-Xu, Ma, Lan, Zhu, Tao, Lobie, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486096/
https://www.ncbi.nlm.nih.gov/pubmed/28617312
http://dx.doi.org/10.3390/ijms18061274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486096/
https://www.ncbi.nlm.nih.gov/pubmed/28617312
http://dx.doi.org/10.3390/ijms18061274

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