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Globular Adiponectin Inhibits Lipopolysaccharide-Primed Inflammasomes Activation in Macrophages via Autophagy Induction: The Critical Role of AMPK Signaling

The inflammasome acts as a key platform for the activation of pro-inflammatory cytokines. Adiponectin exhibits potent anti-inflammatory properties. However, the effect of adiponectin on the modulation of the inflammasome has not been explored. Herein, we show that globular adiponectin (gAcrp) suppre...

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Detalles Bibliográficos
Autores principales: Kim, Mi Jin, Kim, Eun Hye, TiliJa Pun, Nirmala, Chang, Jae-Hoon, Kim, Jung-Ae, Jeong, Jee-Heon, Choi, Dong Young, Kim, Sang-Hyun, Park, Pil-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486097/
https://www.ncbi.nlm.nih.gov/pubmed/28617316
http://dx.doi.org/10.3390/ijms18061275