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Targeting Autophagy in Cancer: Update on Clinical Trials and Novel Inhibitors
Eukaryotes use autophagy as a mechanism for maintaining cellular homeostasis by degrading and recycling organelles and proteins. This process assists in the proliferation and survival of advanced cancers. There is mounting preclinical evidence that targeting autophagy can enhance the efficacy of man...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486101/ https://www.ncbi.nlm.nih.gov/pubmed/28621712 http://dx.doi.org/10.3390/ijms18061279 |