Optimization of Polyplex Formation between DNA Oligonucleotide and Poly(l-Lysine): Experimental Study and Modeling Approach

The polyplexes formed by nucleic acids and polycations have received a great attention owing to their potential application in gene therapy. In our study, we report experimental results and modeling outcomes regarding the optimization of polyplex formation between the double-stranded DNA (dsDNA) and...

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Detalles Bibliográficos
Autores principales: Vasiliu, Tudor, Cojocaru, Corneliu, Rotaru, Alexandru, Pricope, Gabriela, Pinteala, Mariana, Clima, Lilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486112/
https://www.ncbi.nlm.nih.gov/pubmed/28629130
http://dx.doi.org/10.3390/ijms18061291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486112/
https://www.ncbi.nlm.nih.gov/pubmed/28629130
http://dx.doi.org/10.3390/ijms18061291

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