Interactions between a Heparin Trisaccharide Library and FGF-1 Analyzed by NMR Methods

FGF-1 is a potent mitogen that, by interacting simultaneously with Heparan Sulfate Glycosaminoglycan HSGAG and the extracellular domains of its membrane receptor (FGFR), generates an intracellular signal that finally leads to cell division. The overall structure of the ternary complex Heparin:FGF-1:...

Descripción completa

Detalles Bibliográficos
Autores principales: García-Jiménez, María José, Gil-Caballero, Sergio, Canales, Ángeles, Jiménez-Barbero, Jesús, de Paz, José L., Nieto, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486114/
https://www.ncbi.nlm.nih.gov/pubmed/28629128
http://dx.doi.org/10.3390/ijms18061293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486114/
https://www.ncbi.nlm.nih.gov/pubmed/28629128
http://dx.doi.org/10.3390/ijms18061293

Ejemplares similares