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Knockout of Murine Mamld1 Impairs Testicular Growth and Daily Sperm Production but Permits Normal Postnatal Androgen Production and Fertility

MAMLD1 has been implicated in testicular function in both human and mouse fetuses. Although three patients with MAMLD1 mutations were reported to have hypergonadotropic hypogonadism in their teens, the functional significance of MAMLD1 in the postnatal testis remains unclear. Here, we analyzed the p...

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Detalles Bibliográficos
Autores principales: Miyado, Mami, Yoshida, Kaoru, Miyado, Kenji, Katsumi, Momori, Saito, Kazuki, Nakamura, Shigeru, Ogata, Tsutomu, Fukami, Maki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486121/
https://www.ncbi.nlm.nih.gov/pubmed/28629181
http://dx.doi.org/10.3390/ijms18061300