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Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study

The low response rates to immunotherapy in uveal melanoma (UM) sharply contrast with reputable response rates in cutaneous melanoma (CM) patients. To characterize the mechanisms responsible for resistance to immunotherapy in UM, we performed immune profiling in tumors from 10 metastatic UM patients...

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Detalles Bibliográficos
Autores principales: Qin, Yong, Petaccia de Macedo, Mariana, Reuben, Alexandre, Forget, Marie-Andrée, Haymaker, Cara, Bernatchez, Chantale, Spencer, Christine N., Gopalakrishnan, Vancheswaran, Reddy, Sujan, Cooper, Zachary A., Fulbright, Orenthial J., Ramachandran, Renjith, Wahl, Arely, Flores, Esteban, Thorsen, Shawne T., Tavera, Rene J., Conrad, Claudius, Williams, Michelle D., Tetzlaff, Michael T., Wang, Wei-Lien, Gombos, Dan S., Esmaeli, Bita, Amaria, Rodabe N., Hwu, Patrick, Wargo, Jennifer A., Lazar, Alexander J., Patel, Sapna P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486182/
https://www.ncbi.nlm.nih.gov/pubmed/28680759
http://dx.doi.org/10.1080/2162402X.2017.1321187