Stress-dependent opposing roles for mitophagy in aging of the ascomycete Podospora anserina

Mitochondrial dysfunction is causatively linked to organismal aging and the development of degenerative diseases. Here we describe stress-dependent opposing roles of mitophagy, the selective autophagic degradation of mitochondria, in aging and life-span control. We report that the ablation of the mi...

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Detalles Bibliográficos
Autores principales: Knuppertz, Laura, Warnsmann, Verena, Hamann, Andrea, Grimm, Carolin, Osiewacz, Heinz D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Basic Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486364/
https://www.ncbi.nlm.nih.gov/pubmed/28368682
http://dx.doi.org/10.1080/15548627.2017.1303021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486364/
https://www.ncbi.nlm.nih.gov/pubmed/28368682
http://dx.doi.org/10.1080/15548627.2017.1303021

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