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Stress-dependent opposing roles for mitophagy in aging of the ascomycete Podospora anserina
Mitochondrial dysfunction is causatively linked to organismal aging and the development of degenerative diseases. Here we describe stress-dependent opposing roles of mitophagy, the selective autophagic degradation of mitochondria, in aging and life-span control. We report that the ablation of the mi...
Autores principales: | Knuppertz, Laura, Warnsmann, Verena, Hamann, Andrea, Grimm, Carolin, Osiewacz, Heinz D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486364/ https://www.ncbi.nlm.nih.gov/pubmed/28368682 http://dx.doi.org/10.1080/15548627.2017.1303021 |
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