Endothelin-1 promotes hypertrophic remodelling of cardiac myocytes by activating sustained signalling and transcription downstream of endothelin type A receptors

G-protein coupled receptor (GPCR) mediated activation of the MAPK signalling cascade is a key pathway in the induction of hypertrophic remodelling of the heart – a response to pathological cues including hypertension and myocardial infarction. While levels of pro-hypertrophic hormone agonists of GPC...

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Detalles Bibliográficos
Autores principales: Archer, Caroline R., Robinson, Emma L., Drawnel, Faye M., Roderick, H. Llewelyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486433/
https://www.ncbi.nlm.nih.gov/pubmed/28412414
http://dx.doi.org/10.1016/j.cellsig.2017.04.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486433/
https://www.ncbi.nlm.nih.gov/pubmed/28412414
http://dx.doi.org/10.1016/j.cellsig.2017.04.010

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