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Estimation of Nonlinear Adsorption Isotherms in Gradient Elution RP-LC of Peptides in the Presence of an Adsorbing Additive

ABSTRACT: In electrostatic repulsive interaction chromatography, using a charged surface hybrid sorbent carrying positive charges can improve the peak shape of peptides in reversed-phase liquid chromatography (RP-LC), especially in overloaded conditions, compared with standard C(18) sorbents. Howeve...

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Detalles Bibliográficos
Autores principales: Åsberg, Dennis, Leśko, Marek, Leek, Tomas, Samuelsson, Jörgen, Kaczmarski, Krzysztof, Fornstedt, Torgny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486455/
https://www.ncbi.nlm.nih.gov/pubmed/28725083
http://dx.doi.org/10.1007/s10337-017-3298-y