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Assessing tumor vascularization as a potential biomarker of imatinib resistance in gastrointestinal stromal tumors by dynamic contrast-enhanced magnetic resonance imaging

BACKGROUND: Most metastatic gastrointestinal stromal tumors (GISTs) develop resistance to the first-line imatinib treatment. Recently, increased vessel density and angiogenic markers were reported in GISTs with a poor prognosis, suggesting that angiogenesis is implicated in GIST tumor progression an...

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Detalles Bibliográficos
Autores principales: Consolino, Lorena, Longo, Dario Livio, Sciortino, Marianna, Dastrù, Walter, Cabodi, Sara, Giovenzana, Giovanni Battista, Aime, Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486478/
https://www.ncbi.nlm.nih.gov/pubmed/27995483
http://dx.doi.org/10.1007/s10120-016-0672-7