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Slack K(Na) channels influence dorsal horn synapses and nociceptive behavior

The sodium-activated potassium channel Slack (Kcnt1, Slo2.2) is highly expressed in dorsal root ganglion neurons where it regulates neuronal firing. Several studies have implicated the Slack channel in pain processing, but the precise mechanism or the levels within the sensory pathway where channels...

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Detalles Bibliográficos
Autores principales: Evely, Katherine M, Pryce, Kerri D, Bausch, Anne, Lukowski, Robert, Ruth, Peter, Haj-Dahmane, Samir, Bhattacharjee, Arin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486487/
https://www.ncbi.nlm.nih.gov/pubmed/28604221
http://dx.doi.org/10.1177/1744806917714342