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Acute Myelogenous Leukemia Cells Secrete Factors that Stimulate Cellular LDL Uptake via Autocrine and Paracrine Mechanisms

Leukemic cells isolated from most patients with acute myelogenous leukemia (AML) have higher low density lipoprotein (LDL) uptake than normal mononuclear blood cells. Little is known, however, about the mechanism behind the elevated LDL uptake. We investigated if AML cells secrete factors that stimu...

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Detalles Bibliográficos
Autores principales: Bhuiyan, Hasanuzzaman, Masquelier, Michèle, Tatidis, Loukas, Gruber, Astrid, Paul, Christer, Vitols, Sigurd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486594/
https://www.ncbi.nlm.nih.gov/pubmed/28488049
http://dx.doi.org/10.1007/s11745-017-4256-z