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Axonal transport deficits in multiple sclerosis: spiraling into the abyss

The transport of mitochondria and other cellular components along the axonal microtubule cytoskeleton plays an essential role in neuronal survival. Defects in this system have been linked to a large number of neurological disorders. In multiple sclerosis (MS) and associated models such as experiment...

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Detalles Bibliográficos
Autores principales: van den Berg, Robert, Hoogenraad, Casper C., Hintzen, Rogier Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486629/
https://www.ncbi.nlm.nih.gov/pubmed/28315956
http://dx.doi.org/10.1007/s00401-017-1697-7