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Charge Mediated Compaction and Rearrangement of Gas-Phase Proteins: A Case Study Considering Two Proteins at Opposing Ends of the Structure-Disorder Continuum

Charge reduction in the gas phase provides a direct means of manipulating protein charge state, and when coupled to ion mobility mass spectrometry (IM-MS), it is possible to monitor the effect of charge on protein conformation in the absence of solution. Use of the electron transfer reagent 1,3-dicy...

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Detalles Bibliográficos
Autores principales: Jhingree, Jacquelyn R., Bellina, Bruno, Pacholarz, Kamila J., Barran, Perdita E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486678/
https://www.ncbi.nlm.nih.gov/pubmed/28585116
http://dx.doi.org/10.1007/s13361-017-1692-1