Human breast cancer cell-mediated bone collagen degradation requires plasminogen activation and matrix metalloproteinase activity

BACKGROUND: Breast cancer cells frequently metastasize to the skeleton and induce extensive bone destruction. Cancer cells produce proteinases, including matrix metalloproteinases (MMPs) and the plasminogen activator system (PAS) which promote invasion of extracellular matrices, but whether these pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Morgan, Hayley, Hill, Peter A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548674/
https://www.ncbi.nlm.nih.gov/pubmed/15701164
http://dx.doi.org/10.1186/1475-2867-5-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548674/
https://www.ncbi.nlm.nih.gov/pubmed/15701164
http://dx.doi.org/10.1186/1475-2867-5-1

Ejemplares similares