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Pre-symptomatic autoimmunity in rheumatoid arthritis: when does the disease start?

It is well recognised that a state of autoimmunity, in which immunological tolerance is broken, precedes the development of symptoms in the majority of patients with rheumatoid arthritis (RA). For individuals who will later develop seropositive disease, this manifests as autoantibodies directed agai...

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Detalles Bibliográficos
Autores principales: Tracy, Alexander, Buckley, Christopher D., Raza, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486797/
https://www.ncbi.nlm.nih.gov/pubmed/28337522
http://dx.doi.org/10.1007/s00281-017-0620-6