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Pre-symptomatic autoimmunity in rheumatoid arthritis: when does the disease start?
It is well recognised that a state of autoimmunity, in which immunological tolerance is broken, precedes the development of symptoms in the majority of patients with rheumatoid arthritis (RA). For individuals who will later develop seropositive disease, this manifests as autoantibodies directed agai...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486797/ https://www.ncbi.nlm.nih.gov/pubmed/28337522 http://dx.doi.org/10.1007/s00281-017-0620-6 |