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Immunoglobulin M gene association with autoantibody reactivity and type 1 diabetes

Several lines of evidence show that autoimmune responses evolving in type 1 diabetes (T1D) patients include the generation of multi-reactive autoantibody (AutoAb) repertoires, but their role in T1D pathogenesis remains elusive. We tested the hypothesis that variants at the immunoglobulin heavy chain...

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Detalles Bibliográficos
Autores principales: Rolim, Inês, Duarte, Nádia, Barata, Gabriela, Costa, João, Gardete-Correia, Luís, Boavida, José, Duarte, Rui, Raposo, João, Peerally, Zulmira, Catarino, Manuela, Penha-Gonçalves, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486809/
https://www.ncbi.nlm.nih.gov/pubmed/28534223
http://dx.doi.org/10.1007/s00251-017-0999-1