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(89)Zr-Onartuzumab PET imaging of c-MET receptor dynamics

PURPOSE: c-MET and its ligand hepatocyte growth factor are often dysregulated in human cancers. Dynamic changes in c-MET expression occur and might predict drug efficacy or emergence of resistance. Noninvasive visualization of c-MET dynamics could therefore potentially guide c-MET-directed therapies...

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Detalles Bibliográficos
Autores principales: Pool, Martin, Terwisscha van Scheltinga, Anton G. T., Kol, Arjan, Giesen, Danique, de Vries, Elisabeth G. E., Lub-de Hooge, Marjolijn N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486818/
https://www.ncbi.nlm.nih.gov/pubmed/28315949
http://dx.doi.org/10.1007/s00259-017-3672-x