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Insights into the prevalence and underlying causes of clonal variation through transcriptomic analysis in Pichia pastoris
Clonal variation, wherein a range of specific productivities of secreted proteins are observed from supposedly identical transformants, is an accepted aspect of working with Pichia pastoris. It means that a significant number of transformants need to be tested to obtain a representative sample, and...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486821/ https://www.ncbi.nlm.nih.gov/pubmed/28534062 http://dx.doi.org/10.1007/s00253-017-8317-2 |