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Intra-image referencing for simplified assessment of HER2-expression in breast cancer metastases using the Affibody molecule ABY-025 with PET and SPECT

PURPOSE: In phase I/II-studies radiolabelled ABY-025 Affibody molecules identified human epidermal growth factor receptor 2 (HER2) expression in breast cancer metastases using PET and SPECT imaging. Here, we wanted to investigate the utility of a simple intra-image normalization using tumour-to-refe...

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Detalles Bibliográficos
Autores principales: Sandberg, Dan, Tolmachev, Vladimir, Velikyan, Irina, Olofsson, Helena, Wennborg, Anders, Feldwisch, Joachim, Carlsson, Jörgen, Lindman, Henrik, Sörensen, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486836/
https://www.ncbi.nlm.nih.gov/pubmed/28261749
http://dx.doi.org/10.1007/s00259-017-3650-3