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Human CD57(+ )germinal center-T cells are the major helpers for GC-B cells and induce class switch recombination
BACKGROUND: The function of CD57(+ )CD4(+ )T cells, constituting a major subset of germinal center T (GC-Th) cells in human lymphoid tissues, has been unclear. There have been contradictory reports regarding the B cell helping function of CD57(+ )GC-Th cells in production of immunoglobulin (Ig). Fur...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548684/ https://www.ncbi.nlm.nih.gov/pubmed/15694005 http://dx.doi.org/10.1186/1471-2172-6-3 |