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Urokinase plasminogen activator protects cardiac myocytes from oxidative damage and apoptosis via hOGG1 induction

The role of uPA in tissue remodeling and cell migration is already well established. In addition, uPA was reported to stabilize p53, a key cell cycle control, DNA repair and apoptosis initiation protein. We aimed to determine the role of uPA-uPAR signaling towards cell survival or apoptosis in human...

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Detalles Bibliográficos
Autores principales: Hohensinner, Philipp J., Takacs, Nikol, Kaun, Christoph, Thaler, Barbara, Krychtiuk, Konstantin A., Pfaffenberger, Stefan, Aliabadi, Arezu, Zuckermann, Andreas, Huber, Kurt, Wojta, Johann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486847/
https://www.ncbi.nlm.nih.gov/pubmed/28643198
http://dx.doi.org/10.1007/s10495-017-1388-9