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Urokinase plasminogen activator protects cardiac myocytes from oxidative damage and apoptosis via hOGG1 induction
The role of uPA in tissue remodeling and cell migration is already well established. In addition, uPA was reported to stabilize p53, a key cell cycle control, DNA repair and apoptosis initiation protein. We aimed to determine the role of uPA-uPAR signaling towards cell survival or apoptosis in human...
Autores principales: | Hohensinner, Philipp J., Takacs, Nikol, Kaun, Christoph, Thaler, Barbara, Krychtiuk, Konstantin A., Pfaffenberger, Stefan, Aliabadi, Arezu, Zuckermann, Andreas, Huber, Kurt, Wojta, Johann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486847/ https://www.ncbi.nlm.nih.gov/pubmed/28643198 http://dx.doi.org/10.1007/s10495-017-1388-9 |
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