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Benefits and harms of 4-factor prothrombin complex concentrate for reversal of vitamin K antagonist associated bleeding: a systematic review and meta-analysis

Prothrombin complex concentrate (PCC) is used for reversal of vitamin K antagonists (VKA) in patients with bleeding complications. This study aims to assess benefits and harms of 4-factor PCC compared to fresh frozen plasma (FFP) or no treatment in VKA associated bleeding. PubMed, EMBASE and CENTRAL...

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Detalles Bibliográficos
Autores principales: Brekelmans, Marjolein P. A., Ginkel, Kim van, Daams, Joost G., Hutten, Barbara A., Middeldorp, Saskia, Coppens, Michiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486892/
https://www.ncbi.nlm.nih.gov/pubmed/28540468
http://dx.doi.org/10.1007/s11239-017-1506-0