Characterization of gana-1, a Caenorhabditis elegans gene encoding a single ortholog of vertebrate α-galactosidase and α-N-acetylgalactosaminidase

BACKGROUND: Human α-galactosidase A (α-GAL) and α-N-acetylgalactosaminidase (α-NAGA) are presumed to share a common ancestor. Deficiencies of these enzymes cause two well-characterized human lysosomal storage disorders (LSD) – Fabry (α-GAL deficiency) and Schindler (α-NAGA deficiency) diseases. Caen...

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Detalles Bibliográficos
Autores principales: Hujová, Jana, Sikora, Jakub, Dobrovolný, Robert, Poupětová, Helena, Ledvinová, Jana, Kostrouchová, Marta, Hřebíček, Martin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548690/
https://www.ncbi.nlm.nih.gov/pubmed/15676072
http://dx.doi.org/10.1186/1471-2121-6-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC548690/
https://www.ncbi.nlm.nih.gov/pubmed/15676072
http://dx.doi.org/10.1186/1471-2121-6-5

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