Human cyclophilin 40 unravels neurotoxic amyloids

The accumulation of amyloidogenic proteins is a pathological hallmark of neurodegenerative disorders. The aberrant accumulation of the microtubule associating protein tau (MAPT, tau) into toxic oligomers and amyloid deposits is a primary pathology in tauopathies, the most common of which is Alzheime...

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Detalles Bibliográficos
Autores principales: Baker, Jeremy D., Shelton, Lindsey B., Zheng, Dali, Favretto, Filippo, Nordhues, Bryce A., Darling, April, Sullivan, Leia E., Sun, Zheying, Solanki, Parth K., Martin, Mackenzie D., Suntharalingam, Amirthaa, Sabbagh, Jonathan J., Becker, Stefan, Mandelkow, Eckhard, Uversky, Vladimir N., Zweckstetter, Markus, Dickey, Chad A., Koren, John, Blair, Laura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486962/
https://www.ncbi.nlm.nih.gov/pubmed/28654636
http://dx.doi.org/10.1371/journal.pbio.2001336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486962/
https://www.ncbi.nlm.nih.gov/pubmed/28654636
http://dx.doi.org/10.1371/journal.pbio.2001336

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