Environmental change drives accelerated adaptation through stimulated copy number variation

Copy number variation (CNV) is rife in eukaryotic genomes and has been implicated in many human disorders, particularly cancer, in which CNV promotes both tumorigenesis and chemotherapy resistance. CNVs are considered random mutations but often arise through replication defects; transcription can in...

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Detalles Bibliográficos
Autores principales: Hull, Ryan M., Cruz, Cristina, Jack, Carmen V., Houseley, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486974/
https://www.ncbi.nlm.nih.gov/pubmed/28654659
http://dx.doi.org/10.1371/journal.pbio.2001333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486974/
https://www.ncbi.nlm.nih.gov/pubmed/28654659
http://dx.doi.org/10.1371/journal.pbio.2001333

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