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The Role of Fibroblasts in Pancreatic Cancer: Extracellular Matrix Versus Paracrine Factors
BACKGROUND AND AIM: Desmoplasia is a characteristic feature and a suspected mechanism of tumor progression in pancreatic ductal adenocarcinoma (PDAC). Main constituents of the stroma involve cancer-associated fibroblasts (CAFs) and extracellular matrix (ECM). The aim of this study was to dissect the...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487255/ https://www.ncbi.nlm.nih.gov/pubmed/28658650 http://dx.doi.org/10.1016/j.tranon.2017.04.009 |