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The Role of Fibroblasts in Pancreatic Cancer: Extracellular Matrix Versus Paracrine Factors

BACKGROUND AND AIM: Desmoplasia is a characteristic feature and a suspected mechanism of tumor progression in pancreatic ductal adenocarcinoma (PDAC). Main constituents of the stroma involve cancer-associated fibroblasts (CAFs) and extracellular matrix (ECM). The aim of this study was to dissect the...

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Detalles Bibliográficos
Autores principales:	Bolm, Louisa, Cigolla, Simon, Wittel, Uwe A., Hopt, Ulrich T., Keck, Tobias, Rades, Dirk, Bronsert, Peter, Wellner, Ulrich Friedrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2017
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487255/ https://www.ncbi.nlm.nih.gov/pubmed/28658650 http://dx.doi.org/10.1016/j.tranon.2017.04.009

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