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Reduced sensory synaptic excitation impairs motor neuron function via Kv2.1 in spinal muscular atrophy
Behavioral deficits in neurodegenerative diseases are often attributed to the selective dysfunction of vulnerable neurons via cell-autonomous mechanisms. Although vulnerable neurons are embedded in neuronal circuits, the contribution of their synaptic partners to the disease process is largely unkno...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487291/ https://www.ncbi.nlm.nih.gov/pubmed/28504671 http://dx.doi.org/10.1038/nn.4561 |