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Novel small peptides derived from VEGF(125-136): potential drugs for radioactive diagnosis and therapy in A549 tumor-bearing nude mice

Vascular endothelial growth factor receptor (VEGFR) is a critical factor in tumor angiogenesis and has been considered a potential target for receptor-mediated radionuclide imaging and therapy. In this study, we identified two peptides (QKRKRKKSRKKH and RKRKRKKSRYIVLS) derived from VEGF(125-136) tha...

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Detalles Bibliográficos
Autores principales: Zhang, Xiang, Feng, Shibin, Liu, Jie, Li, Qianwei, Zheng, Lei, Xie, Laiping, Li, Hongmin, Huang, Dingde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487319/
https://www.ncbi.nlm.nih.gov/pubmed/28655913
http://dx.doi.org/10.1038/s41598-017-04513-y