Downregulated USP3 mRNA functions as a competitive endogenous RNA of SMAD4 by sponging miR-224 and promotes metastasis in colorectal cancer

Increasing evidence shows that competitive endogenous RNAs (ceRNAs) can affect the expression of other transcripts by sequestering common microRNAs (miRNAs), and participate in tumourigenesis. As a potent tumour suppressor in colorectal cancer (CRC), SMAD4 is regulated by many miRNAs. However, the r...

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Detalles Bibliográficos
Autores principales: Wang, Zaozao, Yang, Jie, Di, Jiabo, Cui, Ming, Xing, Jiadi, Wu, Fan, Wu, Wei, Yang, Hong, Zhang, Chenghai, Yao, Zhendan, Zhang, Nan, Jiang, Beihai, Su, Xiangqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487320/
https://www.ncbi.nlm.nih.gov/pubmed/28655924
http://dx.doi.org/10.1038/s41598-017-04368-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487320/
https://www.ncbi.nlm.nih.gov/pubmed/28655924
http://dx.doi.org/10.1038/s41598-017-04368-3

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