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Ca(2+) ionophores are not suitable for inducing mPTP opening in murine isolated adult cardiac myocytes
Opening of the mitochondrial permeability transition pore (mPTP) plays a major role in cell death during cardiac ischaemia-reperfusion. Adult isolated rodent cardiomyocytes are valuable cells to study the effect of drugs targeting mPTP. This study investigated whether the use of Ca(2+) ionophores (A...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487341/ https://www.ncbi.nlm.nih.gov/pubmed/28655872 http://dx.doi.org/10.1038/s41598-017-04618-4 |