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Ca(2+) ionophores are not suitable for inducing mPTP opening in murine isolated adult cardiac myocytes

Opening of the mitochondrial permeability transition pore (mPTP) plays a major role in cell death during cardiac ischaemia-reperfusion. Adult isolated rodent cardiomyocytes are valuable cells to study the effect of drugs targeting mPTP. This study investigated whether the use of Ca(2+) ionophores (A...

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Detalles Bibliográficos
Autores principales:	Panel, Mathieu, Ghaleh, Bijan, Morin, Didier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487341/ https://www.ncbi.nlm.nih.gov/pubmed/28655872 http://dx.doi.org/10.1038/s41598-017-04618-4

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