Proximal GATA-binding sites are essential for human HSD3B1 gene transcription in the placenta

The enzyme 3β-hydroxysteroid dehydrogenase/isomerase (3β-HSD) is involved in the synthesis of active steroid hormones. Two human 3β-HSD isoforms are expressed in a tissue-specific pattern. HSD3B1 (type I) expression is essential to produce progesterone for pregnancy maintenance. To understand the me...

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Detalles Bibliográficos
Autores principales: Lai, Tsai-Chun, Li, Hsiao-Fang, Li, Yu-Shian, Hung, Pei-Yu, Shyu, Ming-Kwang, Hu, Meng-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487343/
https://www.ncbi.nlm.nih.gov/pubmed/28655875
http://dx.doi.org/10.1038/s41598-017-04133-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487343/
https://www.ncbi.nlm.nih.gov/pubmed/28655875
http://dx.doi.org/10.1038/s41598-017-04133-6

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